Evaluation of Percutaneous Drug Permeation Using a Lateral Sectioning Approach
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منابع مشابه
Formulation and Evaluation of Hydrogel-Thickened Microemulsion For Topical Delivery of Minoxidil
The available minoxidil formulations for topical application suffer with major drawback and requires repeated application. The present study was aimed to investigate the effect of microemulsions and microemulsion based hydrogel-systems (MEHs) for increased percutaneous penetration of minoxidil. Minoxidil microemulsions were developed by conventional titration method using oleic-acid as oil, twe...
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Curcumin is the active component of Curcuma species including C. longa (turmeric). This molecule is well known for its anti-inflammatory effect, which seems to be stronger than that of hydrocortisone. Curcuma species have been used in Asian traditional medicine as topical anti-inflammatory drugs. Curcumin has poor oral bioavailability and its topical application could be of choice, particularly...
متن کاملEnhancement of percutaneous absorption of curcumin (turmeric pigment) by ethanol
Curcumin is the active component of Curcuma species including C. longa (turmeric). This molecule is well known for its anti-inflammatory effect, which seems to be stronger than that of hydrocortisone. Curcuma species have been used in Asian traditional medicine as topical anti-inflammatory drugs. Curcumin has poor oral bioavailability and its topical application could be of choice, particularly...
متن کاملDesign and Evaluation of Hydrogel-Thickened Microemulsion for Topical Delivery of Minoxidil
The available minoxidil formulations for topical application suffer with major drawback having less contact time with the scalp which requires repeated application. Hence, the present study was aimed to investigate the effect of microemulsions and microemulsion based hydrogel systems (MEHs) for increased percutaneous penetration of minoxidil. Minoxidil microemulsions were developed by following...
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A topical preparation containing aceclofenac was developed using an o/w microemulsion system. Isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. Pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (Labrasol) and co-surfactant (plurol oleique) for microemulsion formation. Five different formulations were formul...
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